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The Tottenham defender scored twice as Spurs extended their unbeaten run in away games in the Premier League and delivered Everton their first defeat at Hill Dickinson Stadium.

Everton were undefeated in their last five matches at their new ground at Bramley-Moore Dock, having departed Goodison Park behind after 133 years at the conclusion of the previous campaign.

But Tottenham's leader the Dutchman pounced on two occasions from set-pieces in the opening 45 minutes to put their impressive record at jeopardy, and they were failed to mount a comeback before the midfielder - assisted by ex-Everton forward Richarlison - headed home a final goal to put the game to bed.

Jake O'Brien thought he had levelled the tally a short while after the defender's first goal, directing a powerful header past the Spurs keeper from an set-piece.

The Portuguese striker, meanwhile, failed to convert a number of chances, while Vicario made a series of excellent saves to guarantee Tottenham went five matches on the road without defeat in the Premier League.

But the video assistant referee stepped in, advising the match official to review the score on the pitchside monitor and the official decided that Jack Grealish and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.

The win elevates Thomas Frank's side up to third in the Premier League, five points off local foes and leaders Arsenal.

The Merseyside club stay 14th and are half a dozen points ahead of the relegation zone.

Spurs breakdown: The defender fulfils duties at each end of pitch

Following a uninspiring weekday display in the Champions League against Monaco, where they mustered a only attempts on goal, Frank chose the French striker in attack instead of ex-Everton forward the Brazilian.

The summer signing was unable to make much of an impact before being substituted for Richarlison after an hour on the pitch, but it emerged he proved unnecessary in the end.

Defender the Dutchman converted into an attacking force to be feared.

Tottenham's opening strike came from a well-worked corner routine, with Rodrigo Bentancur heading the ball back across the face of goal for an unmarked Van de Ven to score.

And the captain - filling in as captain in Cristian Romero's absence - added his next goal in first-half stoppage time as he outjumped Jordan Pickford to nod in.

Van de Ven was just as impressive in defence, combining well with his defensive colleague as the pair dealt excellently with the numerous deliveries sent their way by Everton.

Everton analysis: Everton lacking striker's instinct

Everton's recent stadium had been a fortress, but it appears the freshness may have worn off slightly and supporters headed to the gates after the midfielder's final goal for Spurs.

The break in the team's winning streak at home will not be a major worry for the manager, but their striker situation are.

The forward and Thierno Barry - the Everton's pair of recognised centre-forwards - had netted only a single goal combined before Sunday's outing.

And they were failed to contribute to that miserable record on a wet and gloomy evening on Merseyside.

Beto's performance was epitomized when he chose to overhead kick a golden opportunity from close range, despite having space and time to readjust for a more conventional attempt that would have tested Vicario.

Barry, as well, failed to influence the game after replacing Beto in the 65th minute.

It was not for a lack of chance. The majority of the home side's attacks came through the winger and Ndiaye, who tirelessly whipped threatening balls into the Spurs penalty area.

What next for these two sides?

Everton: The team head to Sunderland in the Premier League on Monday, 3 November at 8 PM.

Spurs: The London club go to St James' Park on late October for their next round League Cup tie against the Magpies.